Evaluation of bovine coronavirus in Korean native calves challenged through different inoculation routes

Autor: Hyung-Chul Cho, Youngjun Kim, Yong-Il Cho, Jinho Park, Kyoung-Seong Choi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Veterinary Research, Vol 55, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 1297-9716
DOI: 10.1186/s13567-024-01331-9
Popis: Abstract Bovine coronavirus (BCoV) is a pneumoenteric virus that can infect the digestive and respiratory tracts of cattle, resulting in economic losses. Despite its significance, information regarding BCoV pathogenesis is limited. Hence, we investigated clinical signs, patterns of viral shedding, changes in antibody abundance, and cytokine/chemokine production in calves inoculated with BCoV via intranasal and oral. Six clinically healthy Korean native calves (
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