Report of Dyschromatosis Universalis Heriditaria in Four Members of the Same Family

Autor: Roma Jawane, M Hemapriya, Raja Parthiban
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of Medical Sciences and Health, Vol 3, Iss 3, Pp 29-32 (2017)
Druh dokumentu: article
ISSN: 2394-9481
2394-949X
Popis: Dyschromatosis Universalis Heriditaria (DUH) is an autosomal dominant disorder that usually presents in infancy or early childhood in Asian families and is characterized by pinpoint to pea-sized hypo- and hyper- pigmented macules, distributed in a reticulated pattern over the trunk, abdomen, and limbs, usually sparing the face and palmoplantar surfaces. It was reported initially and mainly in Japan. However, subsequent cases have been reported from other countries. This report describes DUH in four members of the same family. Skin biopsies of representative lesions from all the affected family members were taken and processed for histopathological examination. The tissue sections were stained with hematoxylin and eosin, and also a special stain for melanocytes was performed to arrive at a diagnosis.
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