Renal rickets-practical approach

Autor: Manisha Sahay, Rakesh Sahay
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Indian Journal of Endocrinology and Metabolism, Vol 17, Iss 7, Pp 35-44 (2013)
Druh dokumentu: article
ISSN: 2230-8210
2230-9500
DOI: 10.4103/2230-8210.119503
Popis: Rickets/osteomalacia is an important problem in a tropical country. Many cases are due to poor vitamin D intake or calcium deficient diets and can be corrected by administration of calcium and vitamin D. However, some cases are refractory to vitamin D therapy and are related to renal defects. These include rickets of renal tubular acidosis (RTA), hypophosphatemic rickets, and vitamin D dependent rickets (VDDR). The latter is due to impaired action of 1α-hydroxylase in renal tubule. These varieties need proper diagnosis and specific treatment.
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