Multiple cerebral melanoma metastases with unknown primary tumor location: A case report

Autor:	Liviu Cozma, Delia Tulba, Maria Barsevschi, Cristina Mitu, Laura Dumitrescu, Radu Tanasescu, Bogdan Ovidiu Popescu
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	cerebral metastases unknown primary tumor melanoma braf mutation swi hypointensity fluid-blood level Medicine Neurology. Diseases of the nervous system RC346-429
Zdroj:	Romanian Journal of Neurology, Vol 16, Iss 4, Pp 175-178 (2017)
Druh dokumentu:	article
ISSN:	1843-8148 2069-6094
DOI:	10.37897/RJN.2017.4.9
Popis:	Introduction. Diagnostic and therapeutic approach of multiple cerebral lesions is often challenging. Case report. A 66-year-old man with unremarkable medical history was admitted to our hospital for recent inability and stereotyped movements of the left upper limb. Brain MRI identified eight tumoral masses with contrast enhancement and marked SWI signal loss that displayed increased metabolic activity on 18F-FDG PET/CT scan. Cerebral biopsy led to the diagnosis of melanoma with BRAF V600E mutation. Stereotactic radiosurgery and molecular therapy were planned afterwards. Conclusion. Brain MRI is a useful tool in guiding diagnosis of cerebral metastases of unknown origin.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d87eb211c4094629920990f0268fc29b Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF