Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems

Autor: Christopher M. Bellas, Declan C. Schroeder, Arwyn Edwards, Gary Barker, Alexandre M. Anesio
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-18236-8
Popis: Bacteriophages and their hosts are involved in a constant evolutionary arms race that should lead to divergence between phage genes over time. Here, the authors recruit metagenomic reads to virus reference genomes and genome fragments in samples from cryoconite holes and show that phages with near-identical core genomes maintain diversity by possession of numerous flexible gene modules, where homologous genes present in the pan-genome interchange to create new phage variants.
Databáze: Directory of Open Access Journals