The influence of electrical stimulation (es) of paleocerbellar cortex upon penicillin-induced foci induced in brain cortex of kindled rats
| Autor: | L S Godlevsky, E V Kobolev, O G Ovchinnikova, V F Mustyatsa, G А Drozdova |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | RUDN Journal of Medicine, Vol 0, Iss 1, Pp 31-35 (2010) |
| Druh dokumentu: | article |
| ISSN: | 2313-0245 2313-0261 |
| Popis: | Electrical stimulation (ES) (0,25 ms, 100 Hz, 150-250 mcА) of paleocerebellar cortex (pyramis and culmen) caused the suppression of epileptogenic foci, induced in frontal cortex via application of penicillin solution (16 000 IU/ml) to male Wistar rats in three weeks from the moment of last corazol kindled administration. Antiepileptic effects have been pronounced in form of suppression of amplitude and frequency of spikes as well as in the net shortening of life-span of foci. Lower and higher intensities of ES did not cause suppression of focal epileptogenesis. |
| Databáze: | Directory of Open Access Journals |
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