| Autor: |
Indira Paz-Graniel, Cristina Valle-Hita, Nancy Babio, Lluís Serra-Majem, Jesus Vioque, María Dolores Zomeño, Dolores Corella, Xavier Pintó, Naomi Cano-Ibáñez, Josep A. Tur, Esther Cuadrado-Soto, J.A. Martínez, Andrés Díaz-López, Laura Torres-Collado, Albert Goday, Rebeca Fernández-Carrión, Mariela Nissenshon, Antoni Riera-Mestre, Eva Garrido-Garrido, Cristina Bouzas, Itziar Abete, Lidia Daimiel, Isabel Cornejo-Pareja, Zenaida Vázquez-Ruiz, Nadine Khoury, Karla Alejandra Pérez-Vega, Jordi Salas-Salvadó |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
The Journal of Nutrition, Health and Aging, Vol 28, Iss 9, Pp 100327- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1760-4788 |
| DOI: |
10.1016/j.jnha.2024.100327 |
| Popis: |
Objectives: The evidence on water intake in the prevention of kidney function decline is scarce at population level in well-being individuals at high cardiovascular risk. Therefore, we aimed to longitudinally evaluate the associations between total water intake and subtypes and kidney function, through estimated-Glomerular Filtration Rate (eGFR). Methods: Three-year prospective analysis conducted in 1986 older adults (aged 55–75 year) with overweight/obesity and metabolic syndrome from the PREDIMED-Plus study. Water intake was assessed using validated beverage and food frequency questionnaires. Serum creatinine-based eGFR (SCr-based eGFR; ml/min/1.73 m2) was estimated using the CKD-EPI equation at baseline, one-year and 3-years of follow-up. Mixed-effects linear regression models were fitted to evaluate the associations between baseline total water intake and subtypes, and SCr-based eGFR over 3-years of follow-up. Results: Participants in the highest baseline tertile of total water intake, plain water and water from all fluids showed a lower decrease in SCr-based eGFR after 3-years of follow-up, compared to those in the lowest tertile. Participants with the highest tap water consumption showed a lower SCr-based eGFR decline after 1-year and 3-years of follow-up, in comparerd to participants in the lowest intake category (T3 vs. T1: β: 1.4 ml/min/1.73 m2; 95%CI: 0.5–2.3, β: 1.0; 95%CI: 0.1–2.0, respectively). Conclusions: Plain water rather than other water sources, and especially tap water, was associated with lower kidney function decline assessed through eGFR over 3-years of follow-up, in older individuals at high cardiovascular risk. Trial registration: ISRCTN89898870. Retrospectively registered on 24 July 2014 |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
