Histological and morphometric aspects of ridge preservation with a moldable, in situ hardening bone graft substitute

Autor: Jurišić M., Manojlović-Stojanoski Milica, Andrić M., Koković V., Danilović Vesna, Jurišić Tamara, Brković B.
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Archives of Biological Sciences, Vol 65, Iss 2, Pp 429-437 (2013)
Druh dokumentu: article
ISSN: 0354-4664
1821-4339
DOI: 10.2298/ABS1302429J
Popis: Biphasic calcium phosphates (BCP) are widely used in alveolar ridge regeneration as a porous scaffold for new bone formation. The aim of this case series was to evaluate the regenerative effect of the combination of BCP and polylactide-co-glycolide (PLGA) which can serve as a barrier membrane during bone regeneration. The study included five patients. Four months into the healing period, bone samples were collected for histological and morphometric analyses. The results of morphometric analysis showed that newly formed bone represented 32.2 ± 6.8% of the tissue, 31.9 ± 8.9% was occupied by residual graft and 35.9 ± 13.5% by soft tissue. Active osteogenesis was seen around the particles of the graft. The particles were occupied mostly by immature woven bone and connective tissue. The quality and quantity of newly formed bone, after the use of BCP/PLGA for ridge preservation, can be adequate for successful implant therapy after tooth extraction. [Projekat Ministarstva nauke Republike Srbije, br. OI 175021 i br. OI 173009]
Databáze: Directory of Open Access Journals