| Autor: |
Arbia Talbi, Anne Gaucher, Flavien Bourdreux, Jérôme Marrot, Mohamed L. Efrit, Hédi M’Rabet, Damien Prim |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Molecules, Vol 22, Iss 12, p 2171 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/molecules22122171 |
| Popis: |
A Barbier reaction–Heck arylation sequence from α-bromomethylbutenolide to fused tri and tetracyclic lactones has been developed. The first step involving a Barbier reaction enabled installing ortho-bromoaromatics in α-ylidene γ-lactones. The latter substrates were subjected to intramolecular Heck reaction conditions which selectively afforded 6,5,5 or 6,6,5 fused ring systems depending on the nature of the base employed. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
