| Autor: |
Gulam Mohammed Husain, Mohd Nadeem, Ghazala Javed, Mohd Urooj, Mahe Alam, Muskula Anudeep Reddy, Munawwar Husain Kazmi |
| Jazyk: |
English<br />Spanish; Castilian |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Ars Pharmaceutica, Vol 62, Iss 1, Pp 6-14 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2340-9894 |
| DOI: |
10.30827/ars.v62i1.15432 |
| Popis: |
Abstract Introduction: Khamira Gawzaban Ambari Jadwar Ood Saleeb Wala (KGAJOS) is a polyherbal compound Unani Pharmacopoeial formulation described in traditional Unani texts as Muqawwi-e-Aza-e-Raeesa (tonic for brain, heart, liver and stomach). KGAJOS is reported to possess anxiolytic and antidepressant activity in mice. Though it is used clinically for various neurological conditions, preclinical efficacy of this formulation in learning and memory enhancement / improvement is not established. Method: KGAJOS was evaluated for cognitive function improvement activity using Morris water maze test in C57BL/6 mice. Piracetam was used as positive control for comparison. Anymaze video tracking software was used for tracking the path of mice in pool as per standard protocol. Results: During probe trial in Morris water maze test, a significant increase in time spent in platform quadrant was observed at 1000 and 1500 mg/kg bw of KGAJOS (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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