| Autor: |
Fangfang Lu, Bai Shi, Wei Cao, Huiping Yin, Tianjiao Huang, Kai Zhang, Changsheng Yao |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Tetrahedron Chem, Vol 7, Iss , Pp 100044- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2666-951X |
| DOI: |
10.1016/j.tchem.2023.100044 |
| Popis: |
A novel NHC-catalyzed regiodivergent reaction of ynones with trifluoromethyl ketones consisting of Aldol reactions and intermolecular [3 + 2] annulations has been developed. Employing two different NHC catalysts, various tertiary alcohols and dihyrofuranones containing trifluoromethyl can be obtained in moderate to good yields (35 examples, up to 91% yield). This protocol features mild reaction conditions, high efficiency and broad substrates scope, promoting the development of NHC catalysis and transformations of ynones. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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