Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides

Autor: Tom Guterman, Micha Kornreich, Avigail Stern, Lihi Adler-Abramovich, Danny Porath, Roy Beck, Linda J. W. Shimon, Ehud Gazit
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms13482
Popis: The application of nanofibres formed from monomers of bacterial type IV pili in vitrohas proven to be complex. Here, the authors have overcome this limitation by using a reductionist approach to design a self-assembling pilin-based 20-mer peptide capable of forming a supramolecular beta sheet.
Databáze: Directory of Open Access Journals