A case of synchronous intramucosal gastric carcinoma with multiple lymph node metastases

Autor: En Amada, Hirofumi Kawakubo, Satoru Matsuda, Shuhei Mayanagi, Rieko Nakamura, Tomoyuki Irino, Norihito Wada, Shuji Mikami, Yuko Kitagawa
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Surgical Case Reports, Vol 7, Iss 1, Pp 1-6 (2021)
Druh dokumentu: article
ISSN: 2198-7793
DOI: 10.1186/s40792-021-01149-z
Popis: Abstract Background In Japan, the prevalence of synchronous multiple intramucosal gastric carcinoma is reported to be 5–15%. Here is a case of a synchronous small gastric carcinoma fulfilling the definite indication and curative criteria for endoscopic submucosal dissection with multiple lymph node metastases. Case presentation A Japanese woman in her fifties with a history of endoscopic resection for mucosal poorly differentiated adenocarcinoma was evaluated, with the UICC TNM classification stage being cT1aN0M0 cStageIA. She had undergone total gastrectomy with D1 + lymph node dissection. Histopathological examination revealed 16 individual sporadic lesions in the gastric body, with maximum diameter 3 mm and localization in the lamina propria. Twenty-seven nodes were resected, and metastasis of the carcinoma was revealed in 24 nodes. Conclusions Undifferentiated intramucosal gastric cancer has a relatively high probability of lymph node metastasis; however, synchronous early lesions are often overlooked. Frequent follow-up examinations may increase the detection of multiple gastric cancers.
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