P6.12 AORTIC AND LOCAL CAROTID STIFFNESS: RELATIONSHIP WITH CARDIAC AND VASCULAR ORGAN DAMAGE IN A GENERAL POPULATION SAMPLE IN NORTHERN ITALY

Autor: Anna Paini, Massimo Salvetti, Claudia Agabiti Rosei, Fabio Bertacchini, Giulia Maruelli, Giulia Rubagotti, Efrem Colonetti, Carlotta Donini, Elisa Casella, Enrico Agabiti Rosei, Maria Lorenza Muiesan
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Artery Research, Vol 12 (2015)
Druh dokumentu: article
ISSN: 1876-4401
DOI: 10.1016/j.artres.2015.10.296
Popis: Background: Carotid-femoral pulse wave velocity (aoPWV), the gold-standard measurement of arterial stiffness, has been found associated with cardiac and vascular organ damage. Less information is available with regard to the correlation between local carotid stiffness (CS) and cardiac and vascular preclinical damage. Aim: of the study was to analyse the correlation between aoPWV and CS and cardiac and vascular preclinical organ damage in a middle age general population in Northern Italy (Vobarno Study). Methods: 245 subjects (57%female, age 56±4 years) underwent laboratory examinations, clinic and 24 hours BP measurement, cardiac and carotid ultrasound, aoPWV measurement (Complior-system). CS was determined from the relative stroke change in diameter (measured with a high-resolution echotracking system) and carotid pulse pressure (measured with applanation tonometry) and was expressed in the same dimensions as pulse wave velocity (m/s). Results: Both aoPWV and CS were significantly related with age (r=0.29, p115 g/m2 in men and>95 g/m2 in women)as compared to subjects without LVH (9.1±1.5 vs 8.5±1.4 m/s, p
Databáze: Directory of Open Access Journals
Externí odkaz: