Liquid-based endometrial cytology associated with curettage in the investigation of endometrial carcinoma in postmenopausal women

Autor: Ke Ma, Xi Yang, Rui Chen, Jian Zhao, Ying Dong, Nai-Yi Zhang, Xiu-Hua Ma, Qin-Ping Liao
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Taiwanese Journal of Obstetrics & Gynecology, Vol 55, Iss 6, Pp 777-781 (2016)
Druh dokumentu: article
ISSN: 1028-4559
DOI: 10.1016/j.tjog.2015.09.006
Popis: Objective: The aim of this study was to investigate the diagnostic accuracy of liquid-based endometrial cytology in postmenopausal women, in comparison with histology. Materials and methods: There were 790 postmenopausal women scheduled for hysteroscopy enrolled in this study. After providing informed consent, all patients proceeded sequentially through endometrial cytology, hysteroscopy, and then dilatation and curettage (D&C). Cytology sampling was performed by brushing the uterus cavity using SAP-1 and the sample was prepared to liquid-based smear using SurePath technology. The slides were stained by Papanicolaou method. All cytological diagnoses were correlated with the D&C histological diagnoses. Results: Cytohistological correlations were possible in 567 (71.8%) patients: the D&C was inadequate in 204 (25.8%) patients; the cytology was inadequate in 32 (4.1%) patients; and both were inadequate in 13 (1.6%) patients. SAP-1 provided more sufficient material for cytology than D&C can for histology (p
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