Beta-blockers in the prevention and treatment of ischemic heart disease: Evidence and clinical practice

Autor: Omer Khan, Murti Patel, Anna N Tomdio, Jeffrey Beall, Ion S Jovin
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Heart Views, Vol 24, Iss 1, Pp 41-49 (2023)
Druh dokumentu: article
ISSN: 1995-705X
DOI: 10.4103/heartviews.heartviews_75_22
Popis: Coronary artery disease (CAD) is the most prevalent cardiovascular disease characterized by atherosclerotic plaque buildup that can lead to partial or full obstruction of blood flow in the coronary arteries. Treatment for CAD involves a combination of lifestyle changes, pharmacologic therapy, and modern revascularization procedures. Beta-adrenoceptor antagonists (or beta-blockers) have been widely used for decades as a key therapy for CAD. In this review, prior studies are examined to better understand beta-adrenoceptor antagonist use in patients with acute coronary syndrome, stable coronary heart disease, and in the perioperative setting. The evidence for the benefit of beta-blocker therapy is well established for patients with acute myocardial infarction, but it diminishes as the time from the index cardiac event elapses. The evidence for benefit in the perioperative setting is not strong.
Databáze: Directory of Open Access Journals