Cell Morphology, Viability, Osteocalcin Activity, and Alkaline Phosphatase Activity in Milled versus Unmilled Surface of the Femoral Head

Autor: Kee Hyung Rhyu, Chang Hoon Cho, Kyung Sik Yoon, Young Soo Chun
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Orthopaedic Surgery, Vol 24 (2016)
Druh dokumentu: article
ISSN: 2309-4990
DOI: 10.1177/1602400320
Popis: Purpose To evaluate cellular activity in milled versus unmilled surface of the femoral head in 21 patients who underwent robot-assisted total hip arthroplasty (THA). Methods The femoral head of 21 consecutive patients who underwent robot-assisted THA for osteonecrosis was used. 10 cc of trabecular bone from the entire milled surface was obtained using a curette. The same amount of trabecular bone was obtained at least 1 cm away from the milled surface and served as a matched control. Cell morphology, viability, osteocalcin activity, and alkaline phosphatase activity in milled versus unmilled surface were assessed. Results Cell morphology of the milled or unmilled surface was comparable; cells were smaller in the milled surface. Cell viability was a mean of 40% higher in the milled surface (107.4% vs. 67.2%, p
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