Determination of phenolic compounds and evaluation of cytotoxicity in Plectranthus barbatus using the Allium cepa test

Autor: Kássia Cauana Trapp, Carmine Aparecida Lenz Hister, H. Dail Laughinghouse IV, Aline Augusti Boligon, Solange Bosio Tedesco
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Caryologia, Vol 73, Iss 2 (2020)
Druh dokumentu: article
ISSN: 0008-7114
2165-5391
DOI: 10.13128/caryologia-947
Popis: Plectranthus barbatus, popularly known as Brazilian boldo or false boldo is mainly used for digestive problems. The aim of our study was to evaluate the proliferative and genotoxic potential of aqueous extracts obtained from fresh and dry leaves and stems of P. barbatus using the in vivo Allium cepa test. For the treatments, 6 g of fresh material was first weighed. This was then dried in the microwave, resulting in 0.9 g stems and 0.64 g leaves. The same amount of material was dried naturally at room temperature. We prepared the aqueous extracts by infusion of the leaves and decoction of the stems. Water was used as a negative control and glyphosate 1.5% as a positive control. The extracts were analyzed by high performance liquid chromatography (HPLC). Statistical analysis was performed using the Chi-square and Scott-Knott tests (p
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