Pterygoid Muscle Necrosis Caused by Radiation and Intra-Arterial Cisplatin Infusion Chemotherapy (RADPLAT): A Case Report

Autor: Kazuhiro Miyamoto, Mitsuo Sato, Satoru Koike, Takayuki Kimura, Daisuke Abe, Takahiro Wakasaki, Mutsukazu Kitano, Ryuji Yasumatsu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Case Reports in Oncology, Vol 16, Iss 1, Pp 1475-1481 (2023)
Druh dokumentu: article
ISSN: 1662-6575
DOI: 10.1159/000534939
Popis: Introduction: Radiation and intra-arterial cisplatin infusion chemotherapy (RADPLAT) for advanced maxillary sinus cancer has accumulated evidence as a treatment with fewer complications and better 5-year survival rates. In this study, we report a case in which pterygoid muscle necrosis occurred 6 months following RADPLAT treatment for maxillary sinus cancer. Case Presentation: The 45-year-old woman had a long history of taking immunosuppressants against rheumatoid arthritis (RA) prior to treatment. Although achieving complete response (CR) to RADPLAT, the patient developed trismus (1 fingerbreadth or less) 6 months following treatment. Abscess formation and recurrence were suspected from the imaging findings; however, the biopsy with endoscopy indicated necrotic tissue. Currently, 18 months have passed without cancer recurrence. Although trismus temporarily improved with rehabilitation, the width of the mouth opening is currently a few millimeters, so the patient can only take liquid food. Conclusion: Pterygoid muscle necrosis should be recognized as a new major complication.
Databáze: Directory of Open Access Journals
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