Autor: |
Bing Chen, Chengchao Chu, En Ren, Huirong Lin, Yang Zhang, Peiyu Wang, Hong Yao, Ailin Liu, Gang Liu, Xinhua Lin |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Frontiers in Chemistry, Vol 10 (2022) |
Druh dokumentu: |
article |
ISSN: |
2296-2646 |
DOI: |
10.3389/fchem.2022.870769 |
Popis: |
Metal-ion-based self-assembly supramolecular theranostics exhibit excellent performance in biomedical applications owing to their potential superiorities for simultaneous precise diagnosis, targeted drug delivery, and monitoring the response to therapy in real-time. Specially, the rational designed systems could achieve specific in vivo self-assembly through complexation or ionic interaction to improve tissue-specific accumulation, penetration, and cell internalization, thereby reducing toxicities of drugs in diagnostics and therapy. Furthermore, such imaging traceable nanosystems could provide real-timely information of drug accumulation and therapeutic effects in a non-invasive and safe manner. Herein, the article highlights the recent prominent applications based on the metal ions self-assembly in cancer treatment. This strategy may open up new research directions to develop novel drug delivery systems for cancer theranostics. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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