| Autor: |
Mercedes M. Pérez-Jiménez, José M. Monje-Moreno, Ana María Brokate-Llanos, Mónica Venegas-Calerón, Alicia Sánchez-García, Paula Sansigre, Amador Valladares, Sara Esteban-García, Irene Suárez-Pereira, Javier Vitorica, José Julián Ríos, Marta Artal-Sanz, Ángel M. Carrión, Manuel J. Muñoz |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-020-20269-y |
| Popis: |
Sul-2 is a steroid sulfatase in c.elegans. Here the authors show that, in the absence of sul-2 enzymatic activity, worm lifespan is increased, and that chemical inhibition ameliorates symptoms of neurodegenerative disorders in worms and mice. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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