Age‐specific prevalence and determinants of depression in long‐term breast cancer survivors compared to female population controls

Autor: Daniela Doege, Melissa S. Y. Thong, Lena Koch‐Gallenkamp, Lina Jansen, Heike Bertram, Andrea Eberle, Bernd Holleczek, Ron Pritzkuleit, Annika Waldmann, Sylke R. Zeissig, Hermann Brenner, Volker Arndt
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Cancer Medicine, Vol 9, Iss 22, Pp 8713-8721 (2020)
Druh dokumentu: article
ISSN: 2045-7634
DOI: 10.1002/cam4.3476
Popis: Abstract Background Depression is more prevalent in breast cancer (BC) survivors than in the general population. However, little is known about depression in long‐term survivors. Study objectives were: (1) to compare the age‐specific prevalence of depressive symptoms (a) in BC survivors vs female population controls, (b) in disease‐free BC survivors vs BC survivors with self‐reported recurrence vs controls, and (2) to explore determinants of depression in BC survivors. Methods About 3010 BC survivors (stage I‐III, 5‐16 years post‐diagnosis), and 1005 population controls were recruited in German multi‐regional population‐based studies. Depression was assessed by the Geriatric Depression Scale‐15. Prevalence of mild/severe and severe depression only were estimated via logistic regression, controlling for age and education. Multinomial logistic regression was used to explore determinants of mild and severe depression. Results Compared with population controls, BC survivors were more likely to report mild/severe depression (30.4% vs 23.8%, p = .0003), adjusted for age and education. At all age groups
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