Microbial exopolysaccharide composites with inorganic materials and their biomedical applications: A review

Autor: Vishal Ahuja, Shikha Chauhan, Diptarka Dasgupta, Puneet Wadhwa, Tirath Raj, Yung-Hun Yang, Shashi Kant Bhatia
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Carbohydrate Polymer Technologies and Applications, Vol 7, Iss , Pp 100482- (2024)
Druh dokumentu: article
ISSN: 2666-8939
DOI: 10.1016/j.carpta.2024.100482
Popis: Microbial exopolysaccharides (EPS) are high molecular weight carbohydrate-based materials produced and secreted in response to external environmental stress to protect microbial cells. These molecules also contain non-carbohydrate moieties including acetate, pyruvate, phosphate, and succinate along with sugar molecules. EPS has been incorporated into industrial operations as a gelling, emulsifying, and stabilizing agent to increase viscosity. Besides, these molecules have also shown high biocompatibility, immunomodulatory, antitumor, anti-microbial, and anti-viral activity which suggest their possible applications in healthcare. However, these molecules are facing some commercial shortcomings due to low stability, bioactivity, and poor mechanical and tensile strength in comparison to the required standard. Hence use of composites of EPS with other polymers and moieties has been suggested for higher performance. Especially in the context of inorganic moieties like silver, gold nanomaterials, clay, salts, and minerals will add bioactivity and functional sites for the attachment of drug molecules and other compounds. The current review summarizes the higher physical and chemical characteristics of EPS composites with inorganic materials and their immense potential in the biomedical sector.
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