| Autor: |
Martin Tepel, Christoffer Borst, Claus Bistrup, Niels Marcussen, Nikolaos Pagonas, Felix S Seibert, Robert Arndt, Walter Zidek, Timm H Westhoff |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
PLoS ONE, Vol 9, Iss 11, p e113006 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0113006 |
| Popis: |
ObjectiveCurrent methods do not predict the acute renal allograft injury immediately after kidney transplantation. We evaluated the diagnostic performance of urinary calprotectin for predicting immediate posttransplant allograft injury.MethodsIn a multicenter, prospective-cohort study of 144 incipient renal transplant recipients, we postoperatively measured urinary calprotectin using an enzyme-linked immunosorbent assay and estimated glomerular filtration rate (eGFR) after 4 weeks, 6 months, and 12 months.ResultsWe observed a significant inverse association of urinary calprotectin concentrations and eGFR 4 weeks after transplantation (Spearman r = -0.33; PConclusionsUrinary calprotectin is an early, noninvasive predictor of immediate renal allograft injury after kidney transplantation. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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