Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews

Autor: Yoonkyung Lee, Seon-Jae Ahn, Han-Sang Lee, Yongmoo Kim, Seolah Lee, Hyeyoung Park, Jangsup Moon, Sang Kun Lee, Kon Chu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Encephalitis, Vol 3, Iss 2, Pp 71-77 (2023)
Druh dokumentu: article
ISSN: 2765-4559
2734-1461
DOI: 10.47936/encephalitis.2022.00129
Popis: Several cases of myelin oligodendrocyte glycoprotein (MOG) antibody-associated encephalitis have been reported after coronavirus disease 2019 (COVID-19). In this case, the patient presented with focal status epilepticus with impaired awareness, auditory hallucinations, and incoherent speech after COVID-19. Brain magnetic resonance imaging revealed no specific findings. Cerebrospinal fluid results showed pleocytosis and MOG antibody testing confirmed anti-MOG antibody with live cell-based fluorescence-activated cell sorting assay. The patient was diagnosed with MOG antibody-associated autoimmune encephalitis and treated with intravenous immunoglobulin, rituximab, and tocilizumab. This case occurred presumably due to auto-antibody production following COVID-19.
Databáze: Directory of Open Access Journals