| Autor: |
Craig R. MacNair, Jonathan M. Stokes, Lindsey A. Carfrae, Aline A. Fiebig-Comyn, Brian K. Coombes, Michael R. Mulvey, Eric D. Brown |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-018-02875-z |
| Popis: |
The plasmid-borne mcr-1 gene confers resistance to the antibiotic colistin. Here, MacNair et al. show that mcr-1 positive bacteria are however susceptible to colistin-mediated disruption of the outer membrane, and can be killed in vitro and in vivo by combining colistin with other antibiotics. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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