Ethyl 3-(4-fluorophenyl)-6-methyl-4-oxo-2-(1-cyclohexylamino)-3,4-dihydrofuro[2,3-d]pyrimidine-5-carboxylate
| Autor: | Yong Sun, Guo-Ping Zeng, Yang-Gen Hu |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: | |
| Zdroj: | Acta Crystallographica Section E, Vol 64, Iss 1, Pp o311-o312 (2008) |
| Druh dokumentu: | article |
| ISSN: | 16005368 1600-5368 |
| DOI: | 10.1107/S1600536807066780 |
| Popis: | In the crystal structure of the title compound, C22H24FN3O4, the two fused rings of furo[2,3-d]pyrimidine form a dihedral angle of 0.88 (13)°. The attached benzene ring is twisted with respect to the heterocyclic pyrimidinone ring, making a dihedral angle of 75.07 (12)°. The cyclohexyl ring shows a distorted chair conformation. The molecular structure is stabilized by intramolecular C—H...O and C—H...N hydrogen-bonding interactions. The crystal packing is mainly stabilized by C—H...π hydrogen-bond interactions. Further stability is provided by C—F...π and C—O...π stacking interactions. |
| Databáze: | Directory of Open Access Journals |
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