| Autor: |
Thiago Ferreira de Souza, Thiago Quinaglia Silva, Lígia Antunes-Correa, Zsofia D. Drobni, Felipe Osório Costa, Sergio San Juan Dertkigil, Wilson Nadruz, Fabrício Brenelli, Andrei C. Sposito, José Roberto Matos-Souza, Otávio Rizzi Coelho, Tomas G. Neilan, Michael Jerosch-Herold, Otávio Rizzi Coelho-Filho |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-021-96630-y |
| Popis: |
Abstract There are limited data on the effects of anthracyclines on right ventricular (RV) structure, function, and tissue characteristics. The goal of this study was to investigate the effects of anthracyclines on the RV using cardiac magnetic resonance (CMR). This was a post-hoc analysis of a prospective study of 27 breast cancer (BC) patients (51.8 ± 8.9 years) using CMR prior, and up to 3-times after anthracyclines (240 mg/m2) to measure RV volumes and mass, RV extracellular volume (ECV) and cardiomyocyte mass (CM). Before anthracyclines, LVEF (69.4 ± 3.6%) and RVEF (55.6 ± 9%) were normal. The median follow-up after anthracyclines was 399 days (IQR 310–517). The RVEF reached its nadir (46.3 ± 6.8%) after 9-months (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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