| Autor: |
Julián Pérez-Ocampo, Oscar Vergara-Serpa, Carlos Jaime Velásquez-Franco, Natalia A Taborda, Lina M Yassin, Juan C Hernandez |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Lupus Science and Medicine, Vol 11, Iss 2 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2053-8790 |
| DOI: |
10.1136/lupus-2024-001242 |
| Popis: |
Objective To explore the potential associations between high-density lipoprotein (HDL) levels and inflammasome components in the context of systemic lupus erythematosus (SLE).Methods A cross-sectional study was conducted. A group of 50 patients with SLE and 50 healthy controls matched by sex and similar age ranges were enrolled. Serum HDL cholesterol (HDL-C) and C reactive protein (CRP) levels were quantified. Serum cytokine levels, including IL-1β and IL-6, were determined by ELISA. The gene expression of inflammasome-related genes in peripheral blood mononuclear cells was measured by quantitative real-time PCR.Results HDL-C levels were lower in the patients with SLE (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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