| Autor: |
Bi-xia Yang, Hua Zhou, Min Yang |
| Jazyk: |
čínština |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Linchuang shenzangbing zazhi, Vol 23, Iss 11, Pp 951-956 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1671-2390 |
| DOI: |
10.3969/j.issn.1671-2390.2023.11.011 |
| Popis: |
As an important member of IL-1 family, interleukin 36 (IL-36) is a key regulator of inflammation. Its proinflammatory agonists are composed of IL-36α, IL-36β and IL-36γ while its antagonists include IL-36Ra and IL-38. And co-receptor of IL-36 subfamily is IL-36 receptor (IL-36R). An imbalance of IL-36 agonists and antagonists may lead to the development of skin diseases, intestinal diseases, lung diseases and tumors. In recent years, many studies have confirmed that IL-36 is correlated closely with the occurrence and development of kidney diseases. This review focused on the structure, biological function, regulatory mechanism and role of IL-36 in kidney disease |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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