| Autor: |
Dinu Sorin, Țârdei Grațiela, Ceaușu Emanoil, Florescu Simin Aysel, Micu Laurențiu, Ecobici Alina Monica, Mihăilă Mariana, Oprișan Gabriela |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Romanian Journal of Laboratory Medicine, Vol 26, Iss 4, Pp 443-449 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2284-5623 |
| DOI: |
10.2478/rrlm-2018-0029 |
| Popis: |
Background: Severe complications of chronic hepatitis C – i.e. cirrhosis and hepatocellular carcinoma – are important causes of morbidity and mortality worldwide. Despite the overwhelming rates of sustained virologic response achieved after therapy with different combinations of direct-acting antiviral drugs (DAAs), treatment failure is still recorded, and is due to the mutations harboured by hepatitis C virus (HCV) resistance associated variants (RAVs) selected during therapy. Baseline RAVs testing was found significant for guiding treatment in the cases of treatment failure and, sometimes, in naïve patients. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
