Assessment of a strategy combining ambulatory blood pressure, adherence monitoring and a standardised triple therapy in resistant hypertension

Autor: Erietta Polychronopoulou, Michel Burnier, Georg Ehret, Renate Schoenenberger-Berzins, Maxime Berney, Belen Ponte, Paul Erne, Murielle Bochud, Antoinette Pechère-Bertschi, Gregoire Wuerzner
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Blood Pressure, Vol 30, Iss 6, Pp 332-340 (2021)
Druh dokumentu: article
ISSN: 0803-7051
1651-1999
08037051
DOI: 10.1080/08037051.2021.1907174
Popis: Purpose Poor adherence to drug therapy and inadequate drug regimens are two frequent factors responsible for the poor blood pressure (BP) control observed in patients with apparent resistant hypertension. We evaluated the efficacy of an antihypertensive management strategy combining a standardised therapy with three long acting drugs and electronic monitoring of drug adherence in patients with apparent resistant hypertension. Materials and Methods In this multicentric observational study, adult patients with residual hypertension on 24 h ambulatory BP monitoring (ABMP) despite the use of three or more antihypertensive drugs could be included. Olmesartan/amlodipine (40/10 mg, single pill fixed-dose combination) and chlorthalidone (25 mg) were prescribed for 3 months in two separated electronic pills boxes (EPB). The primary outcome was 24 h ambulatory systolic BP (SBP) control at 3 months, defined as mean SBP
Databáze: Directory of Open Access Journals
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