Successful Treatment of Klebsiella pneumoniae Harboring a Klebsiella pneumoniae Carbapenemase Isolated from Lumbar Wound Infection and Blood in a Patient with Hardware Retention

Autor: Alan Bulbin, Carol Bono, Tena Philp, Noriel Mariano, Carl Urban
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Case Reports in Infectious Diseases, Vol 2017 (2017)
Druh dokumentu: article
ISSN: 2090-6625
2090-6633
53647548
DOI: 10.1155/2017/9028543
Popis: Infections caused by carbapenem-resistant Enterobacteriaceae, especially carbapenemase producing Klebsiella pneumoniae, represent an urgent threat as outlined by the Centers for Disease Control and Prevention (CDC). We present a 66-year-old male with spinal stenosis who underwent elective L2-pelvis posterior spinal fusion at an outside institution and rapidly developed a complicated infection with Klebsiella pneumoniae harboring Klebsiella pneumoniae carbapenemase. This is the first described case of a patient with Klebsiella pneumoniae harboring Klebsiella pneumoniae carbapenemase causing postoperative lumbar wound infection and bacteremia, successfully treated with ceftazidime-avibactam in combination with additional synergistic antibacterials and without hardware removal.
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