Two new compounds from leaves of Capparis dongvanensis (Sy, B. H. Quang & D. V. Hai) and inhibition activities

Autor: Van Khang Pham, Hiep Hoang Phu, Trung Tu Quang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Open Chemistry, Vol 21, Iss 1, Pp p. 433-50 (2023)
Druh dokumentu: article
ISSN: 2391-5420
DOI: 10.1515/chem-2022-0317
Popis: In continuation of the research, the phytochemical investigation of Capparis dongvanensis (Sy, B. H. Quang & D. V. Hai) (Capparaceae). In this work, we described the isolation and identification of two novel polycyclic compounds Capparisone A (1) and Capparisone B (2). The structures of these compounds were determined based on NMR spectral data and mass spectrometry. Furthermore, we evaluated the inhibitory activities of isolated compounds from C. dongvanensis leaves against five cancer cell lines, the results showed that isolated compounds exhibited good activities on four cancer cell lines. Otherwise, two isolated compounds 1 and 2 and EA extract also exhibited the anti-oxidant activity in the DPPH free radical scavenging assay.
Databáze: Directory of Open Access Journals