Can restrictive filling pattern on dobutamine stress echocardiography predict recovery of left ventricular systolic function after valve replacement in patients with low flow-low gradient aortic stenosis?

Autor: Ahmed El Zayat, Ali Refaat, Ehab Sobhy, Amir Farouk
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: The Egyptian Heart Journal, Vol 67, Iss 2, Pp 99-105 (2015)
Druh dokumentu: article
ISSN: 1110-2608
DOI: 10.1016/j.ehj.2014.04.001
Popis: Background: Low flow/low gradient severe aortic stenosis continues to be a common medical problem with spontaneous dismal prognosis if left untreated. Relationship between improvement and persistence of restrictive filling pattern (that is present on baseline echocardiography) on DSE (dobutamine stress echocardiography) and recovery of LV systolic function after AVR has not been studied before. Objective: We sought to clarify the relationship between improvement and persistence of restrictive filling pattern (that is present on baseline echocardiography) on DSE and recovery of LV systolic function after AVR. Patients and methods: Thirty patients with LF/LG severe AS and restrictive filling pattern on baseline echocardiogram were divided into two groups. Group I included 17 patients with improved diastolic functional class during DSE, and group II included 13 patients with persistent restrictive pattern on DSE study. All patients had a contractile reserve and had AVR afterward. Results: All patients had restrictive filling pattern. No significant difference was found between both groups regarding AVA, mean transaortic gradient, SV, LVEF, E/A ratio, IVRT, DT, S/D ratio, LV septal thickness or LVEDD (p > 0.05). On DSE, group I patients had a significantly more rise in both EF and SV (49.2 ± 5.4% in group I compared to 42.5 ± 6.9% in group II and 66 ± 9 compared to 58 ± 9 ml respectively, p
Databáze: Directory of Open Access Journals