Ang-2, Tie-2, and Ang-2/Tie-2 ratio serum levels as diagnostic and prognostic biomarkers of sepsis in critically ill patients

Autor: Szederjesi János, Georgescu Anca, Santini Ario, Almásy Emőke, Lazar Alexandra, Hutanu Adina, Copotoiu Sanda-Maria, Azamfirei Leonard
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Romanian Journal of Laboratory Medicine, Vol 24, Iss 2, Pp 187-199 (2016)
Druh dokumentu: article
ISSN: 2284-5623
DOI: 10.1515/rrlm-2016-0007
Popis: Sepsis represents one the main cause of death in patients admitted to the intensive care. Biomarkers offer an alternative approach to the diagnostic and prognostic evaluation and improve the outcomes. Angiopoietin 2 (Ang-2) and Tyrosine kinase 2 (Tie-2) are biomarkers which may be involved in sepsis, Ang-2 being responsible for vascular remodelling while Tie-2 is their endothelial receptor.
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