Subclinical vascular, hemodynamic and arterial stiffness changes in adults with cystic fibrosis: cross-sectional observational study

Autor:	Bruno Porto Pessoa, Marcelo Velloso, Érika Pereira Inácio, Claudineia de Oliveira Otoni, Marcelo Bicallho de Fuccio, Bruno Almeida Rezende, Maria Glória Rodrigues-Machado
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Cystic fibrosis Hemodynamics Vascular stiffness Cardiovascular diseases Medicine Science
Zdroj:	Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-024-63904-0
Popis:	Abstract Cardiovascular diseases can be an emerging complication in cystic fibrosis (CF), as the median life expectancy has improved considerably. The objective of this study was to compare vascular, hemodynamic parameters and arterial stiffness in adult CF patients with healthy participants pared by sex and age, and to assess the factors associated with arterial stiffness in the CF group. This is a cross-sectional observational study. The evaluation of cardiovascular parameters was performed non-invasively using Mobil-O-Graph. 36 individuals with CF and 35 controls were evaluated. The mean arterial pressure (96.71 ± 10.98 versus 88.61 ± 7.40 mmHg, p = 0.0005), cardiac output (4.86 ± 0.57 versus 4.48 ± 0.44 L/min, p = 0.002) and systolic volume (64.30 ± 11.91 versus 49.02 ± 9.31 ml, p
Databáze:	Directory of Open Access Journals
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