Clinical follow-up study of SARS-CoV-2 Omicron infection

Autor: KANG Xiaoyu, ZHANG Lin, WANG Liangliang, YAN Rui, WANG Jiuping, CHEN Zhangqian
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Shanghai yufang yixue, Vol 36, Iss 1, Pp 25-29 (2024)
Druh dokumentu: article
ISSN: 1004-9231
DOI: 10.19428/j.cnki.sjpm.2024.23006
Popis: ObjectiveTo observe the clinical course and explore the risk factors for SARS-CoV-2 RNA negative conversion duration (NCD) in asymptomatic and mild-symptomatic patients infected with the SARS-CoV-2 Omicron variant.MethodsClinical data were collected from 244 confirmed cases of corona virus disease (COVID-19) with Omicron variant infection admitted to a temporal makeshift hospital in Shanghai from April 9, 2022 to May 20, 2022. Demographic and clinical data were analyzed, with a primary focus on the time of COVID-19 nucleic acid conversion. Univariate and multivariate Cox regression analysis were used to determine identify risk factors associated with NCD.ResultsThe median duration of negative RNA conversion was 9 days (ranged 7‒12 days). The percentage of patients with positive nucleic acid results on the 5th, 7th, 10th, and 14th days after confirmed infection was 68.4%, 47.1%, 20.1%, and 5.7%, respectively. Kaplan-Meier curves indicated a median nucleic acid conversion time of 12 days (ranged 10‒14 days) for patients with hypertension, 9 days (ranged 7‒11 days) in patients without hypertension, and 11 days (ranged 9‒13 days) for patients aged ≥60 years, and 9 days (ranged 7‒11 days) for patients aged
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