Microwave-assisted synthesis of novel 5-trichloromethyl-4,5-dihydro-1H-1-pyrazole methyl esters under solvent free conditions
| Autor: | Martins Marcos A. P., Beck Paulo, Machado Pablo, Brondani Sergio, Moura Sidnei, Zanatta Nilo, Bonacorso Helio G., Flores Alex F. C. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: | |
| Zdroj: | Journal of the Brazilian Chemical Society, Vol 17, Iss 2, Pp 408-411 (2006) |
| Druh dokumentu: | article |
| ISSN: | 0103-5053 1678-4790 |
| Popis: | Twelve novel 5-trichloromethyl-4,5-dihydro-1H-1-pyrazole ethyl esters have been synthesized in good yields (70-98%) by using environmentally benign microwave induced techniques. The compounds were synthesized from the cyclocondensation of 1,1,1-trichloro-4-alkoxy-3-alken-2-ones [CCl3C(O)C(R²)=C(R¹ )OR, where R, R² = H, alkyl; R¹ = H, alkyl and aryl] with hydrazine methyl carboxylate. The advantages obtained by the using of microwave irradiation under solvent-free conditions, rather than a conventional method, were demonstrated. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|