Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface

Autor: Eric M. Trautmann, Daniel J. O’Shea, Xulu Sun, James H. Marshel, Ailey Crow, Brian Hsueh, Sam Vesuna, Lucas Cofer, Gergő Bohner, Will Allen, Isaac Kauvar, Sean Quirin, Matthew MacDougall, Yuzhi Chen, Matthew P. Whitmire, Charu Ramakrishnan, Maneesh Sahani, Eyal Seidemann, Stephen I. Ryu, Karl Deisseroth, Krishna V. Shenoy
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-23884-5
Popis: Surface two-photon imaging of the brain cannot access somatic calcium signals of neurons from deep layers of the macaque cortex. Here, the authors present an implant and imaging system for chronic motion-stabilized two-photon imaging of dendritic calcium signals to drive an optical brain-computer interface in macaques.
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