Associations of physical activity intensity with incident cardiovascular diseases and mortality among 366,566 UK adults

Autor: Xuanwen Mu, Shuangyan Liu, Mingjian Fu, Mengyun Luo, Ding Ding, Liangkai Chen, Kuai Yu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Behavioral Nutrition and Physical Activity, Vol 19, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 1479-5868
DOI: 10.1186/s12966-022-01393-y
Popis: Abstract Background The associations of the proportion of vigorous physical activity (VPA) to moderate to vigorous physical activity (MVPA) with incident cardiovascular disease (CVD) and all-cause mortality are unclear. Methods The present study included 366,566 participants (aged 40–69 years) without baseline CVD from the UK biobank during 2006 to 2010. Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for risks of outcomes. Results During a median 11.8 years of follow-up, among 366,566 participants (mean age [SD]: 56.0 [8.1]), 31,894 incident CVD and 19,823 total deaths were documented. Compared with no VPA, 0%-30% of VPA to MVPA was associated with 12% and 19% lower risks of incident CVD (HR, 0.88 [95% CI, 0.86–0.91]) and all-cause mortality (HR, 0.81 [95% CI, 0.78–0.84]), respectively. Furthermore, we found that the maximum reduction of risks of incident CVD and all-cause mortality occurred at performing approximately 30% of VPA to MVPA (P
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