Kikuchi-Fujimoto disease can present as delayed lymphadenopathy after COVID-19 vaccination
| Autor: | Takeru Kashiwada, Yoshinobu Saito, Yasuhiro Terasaki, Yukari Shirakura, Kaoruko Shinbu, Toru Tanaka, Yosuke Tanaka, Masahiro Seike, Akihiko Gemma |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Human Vaccines & Immunotherapeutics, Vol 18, Iss 5 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2164-5515 2164-554X 21645515 |
| DOI: | 10.1080/21645515.2022.2071080 |
| Popis: | Following COVID-19 vaccination, ipsilateral axillary and cervical lymphadenopathy may occur, called vaccine-related hypermetabolic lymphadenopathy, which is considered reactive lymphadenopathy. We report here a case of Kikuchi-Fujimoto disease, which occurred three months after vaccination with COVID-19 vaccine. The patient had cervical and axillary lymph node enlargement and a short-term fever that resolved spontaneously after the first and second vaccines. On the 90th day after the first vaccination, the patient developed a high fever and pathologically diagnosed necrotizing lymphadenitis in the axilla, which was diagnosed as Kikuchi-Fujimoto disease. Gallium scintigraphy showed localized swelling and strong uptake in the ipsilateral axilla. It implies the possibility of Kikuchi-Fujimoto Disease in axillary drainage lymph nodes in association with COVID-19 vaccine. Although only a few cases have been reported so far, this case is novel because of its later onset and diagnosis based on pathological and gallium scintigraphy imaging findings. |
| Databáze: | Directory of Open Access Journals |
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