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Objective To systematically evaluate the clinical efficacy and safety of Chinese herbal compound in the treatment of diabetes with insomnia in a randomized controlled trial. Methods The medical databases CNKI,VIP,Wanfang,PubMed,EMBase,and The Cochrane Library were searched to collect and evaluate randomized controlled trial studies that met the inclusion criteria as of February 2023,and relevant data were extracted and analyzed according to outcome measures such as treatment response rate,Pittsburgh sleep quality index(PSQI) scale score,fasting plasma glucose(FPG),hemoglobin A1c(HbA1c),and 2 h postprandial blood glucose(2hPBG). Meta-analysis was performed using Review Manager 5.4 software. Results Thirteen articles met the criteria,and a total of 1 183 cases were included,including 599 cases in the experimental group and 584 cases in the control group.Meta-analysis showed that the treatment response rate,PSQI scale score,FPG,HbA1c and 2hPBG levels in the Chinese herbal compound group were better than those in the Western medicine control group after intervening diabetic patients with insomnia. Conclusion Meta-analysis results suggest that Chinese herbal compound is superior to western medicine in improving diabetes with insomnia. |
