The Cerebral Arterial Wall in the Development and Growth of Intracranial Aneurysms

Autor: Pasquale Marco Abbate, A. T. M. Hasibul Hasan, Alice Venier, Vincent Vauclin, Silvia Pizzuto, Alessandro Sgreccia, Federico Di Maria, Oguzhan Coskun, Katsuhiro Mizutani, Georges Rodesch, Arturo Consoli
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Applied Sciences, Vol 12, Iss 12, p 5964 (2022)
Druh dokumentu: article
ISSN: 2076-3417
DOI: 10.3390/app12125964
Popis: A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm’s development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.
Databáze: Directory of Open Access Journals