Evaluation of the anti-osteoporotic effect of Ginkgo biloba L. in Wistar rats with glucocorticoid-induced-osteoporosis by bone densitometry using dual-energy x-ray absorptiometry (DEXA) and mechanical testing
| Autor: | LEDA M.F. LUCINDA, BEATRIZ J.V. AARESTRUP, MAYCON M. REBOREDO, THAIS D.A. PAINS, RAPHAEL Z. CHAVES, JOÃO E.P. REIS, MÁRIO J.Q. LOUZADA, MARTHA O. GUERRA |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Anais da Academia Brasileira de Ciências, Iss 0 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1678-2690 0001-3765 |
| DOI: | 10.1590/0001-3765201720160479 |
| Popis: | ABSTRACT Evaluate the effect of the extract of Ginkgo biloba in the bone alkaline phosphatase, bone mineral density, in the mechanical properties of the tibia in rats with glucocorticoid-induced-osteoporosis. After osteoporosis induction, the rats were divided into five groups: Osteoporosis; EGb1 (28 mg/Kg); EGb2 (56 mg/Kg); alendronate (0.2 mg/animal) and control. The animals were treated during 20 and 30 days. The control group was compared with the osteoporosis’s (Student’s t-test), while the other were analyzed by ANOVA test followed by Tukey/Dunnett’T3 (p |
| Databáze: | Directory of Open Access Journals |
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