Unmet Needs for the Treatment of Chronic Hepatitis E Virus Infection in Immunocompromised Patients

Autor:	Nassim Kamar, Arnaud Del Bello, Florence Abravanel, Qiuwei Pan, Jacques Izopet
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	hepatitis E virus organ transplantation ribavirin treatment needs Microbiology QR1-502
Zdroj:	Viruses, Vol 14, Iss 10, p 2116 (2022)
Druh dokumentu:	article
ISSN:	1999-4915
DOI:	10.3390/v14102116
Popis:	Hepatitis E virus (HEV) is the most prevalent hepatitis virus worldwide. Genotypes 3 (HEV3) and 4 (HEV4) as well as rat HEV can lead to chronic hepatitis E and cirrhosis in immunosuppressed patients. Within the last decade, several options for treating chronic hepatitis have been developed and have achieved a sustained virological response. However, there are still unmet needs such as optimizing immunosuppression to allow HEV clearance with or without ribavirin, as well as alternative therapies to ribavirin that are discussed in this paper.
Databáze:	Directory of Open Access Journals
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