Pharmacokinetics of solifenacin in pediatric populations with overactive bladder or neurogenic detrusor overactivity

Autor: Stacey Tannenbaum, Martin den Adel, Walter Krauwinkel, John Meijer, Adriana Hollestein‐Havelaar, Frank Verheggen, Donald Newgreen
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Pharmacology Research & Perspectives, Vol 8, Iss 6, Pp n/a-n/a (2020)
Druh dokumentu: article
ISSN: 2052-1707
DOI: 10.1002/prp2.684
Popis: Abstract The aim of this investigation was to characterize and compare the pharmacokinetics (PK) of the antimuscarinic drug solifenacin in pediatric patients with overactive bladder (OAB) or neurogenic detrusor overactivity (NDO) utilizing data from three phase III trials. LION was a placebo‐controlled, 12‐week trial in children (5–
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