ARNI Versus Perindopril for Remodeling in HFrEF. A Cohort Study
Autor: | Noor Muhammad Azlan Shah Bin Atan MBBS, Mohd Firdaus Bin Hadi MBBS, Victoria Wen Yeng Teoh, Mahmoud Danaee PhD, Alexander Loch MBBS, MRCP, MCEM, MD |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Journal of Cardiovascular Pharmacology and Therapeutics, Vol 28 (2023) |
Druh dokumentu: | article |
ISSN: | 1940-4034 10742484 |
DOI: | 10.1177/10742484231195019 |
Popis: | Introduction: Ventricular remodeling is a mal-adaptive process. Both angiotensin-converting enzyme inhibitors and sacubitril/valsartan have been shown to reverse remodeling in mostly uncontrolled observational studies. There is a lack of head-to-head studies. Methods: This cohort study compares the remodeling effects of angiotensin receptor blockers combined with a neprilysin inhibitor (ARNI) and perindopril in heart failure with reduced ejection fraction (HFrEF) patients between January 2017 and December 2020. Inclusion criteria: (i) age > 18 years, (ii) recent diagnosis of de-novo HFrEF (EF |
Databáze: | Directory of Open Access Journals |
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