Magnetic resonance imaging in size assessment of invasive breast carcinoma with an extensive intraductal component

Autor: Bult Peter, Boetes Carla, Schouten van der Velden Arjan P, Wobbes Theo
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: BMC Medical Imaging, Vol 9, Iss 1, p 5 (2009)
Druh dokumentu: article
ISSN: 1471-2342
DOI: 10.1186/1471-2342-9-5
Popis: Abstract Background Breast-conserving treatment of invasive breast carcinoma with an extensive intraductal component (EIC) is associated with DCIS-involved surgical margins and therefore it has an increased recurrence rate. EIC is a non-palpable lesion of which the size is frequently underestimated on mammography. This study was undertaken to evaluate the accuracy of MRI in size assessment of breast cancer with EIC. Methods 23 patients were identified and the mammographic (n = 21) and MR (n = 23) images were re-reviewed by a senior radiologist. Size on MR images was compared with histopathological tumour extent. Results The correlation of radiological size with histopathological size was r = 0.20 in mammography (p = 0.39) compared to r = 0.65 in MRI (p < 0.01). Mammography underestimated histopathological tumour size in 62%. MR images over- or underestimated tumour size in 22% and 30% of the cases, respectively. In poorly differentiated EIC, MRI adequately estimated the extent more often compared to moderately differentiated EIC (60% versus 25%, respectively). Conclusion Size assessment of MRI imaging was more accurate compared to mammography. This was predominantly true for poorly differentiated EIC.
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