| Autor: |
Lijun Hao, Jiong Yang, Biyao Lian, Chunyan Yin, Yanfeng Xiao, Yuesheng Liu |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Immunology, Vol 15 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1664-3224 |
| DOI: |
10.3389/fimmu.2024.1455025 |
| Popis: |
ObjectiveTo investigate serum TL1A levels and their correlation with Th17 cells, IL-17, and IL-21 in children with Graves’ disease (GD).MethodsThirty-seven children (12 males and 25 females) aged 9-14 years with newly diagnosed and untreated GD were enrolled in this study. Serum TL1A, IL-17, and IL-21 levels were measured using enzyme-linked immunosorbent assay (ELISA). The percentage of Th17 cells in peripheral blood was determined by flow cytometry. The correlation between serum TL1A levels and Th17 cells, IL-17, and IL-21 was analyzed using Pearson’s correlation coefficient.ResultsSerum TL1A levels and the percentage of Th17 cells were significantly higher in children with GD compared to healthy controls (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
